Drug

Clesacostat

As of the edition of 20 October 2026, Clesacostat is a small molecule: in active development; acts on ACACA and ACACB.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2019
Kind
Small molecule
Registered trials
9, 0 stopped early
Disease areas
Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
ACACBAcetyl-CoA carboxylase 2O00763
ACACAAcetyl-CoA carboxylase 1Q13085

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 16600
Phase 23300
All trials9

Who ran its trials

CompanyRoleYears
PfizerLead sponsor of trials2016 to now