Dopamine
As of the edition of 20 October 2026, Dopamine is a small molecule: marketed, first approved in 1981 (ES); acts on ADRB1.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 2024
- Kind
- Small molecule
- Brand name
- Intropin
- First approved
- 1 December 1981 (ES)
- Approvals on record
- 31 in 5 regions
- Holder of the most recent approval
- BrePco Biopharma; 12 holders in all
- Registered trials
- 28, 4 stopped early
- Disease areas
- Heart and blood vessels; Nervous system; Infections; Inherited and neonatal; Lungs and airways; Pregnancy and women's health
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Companies that need a new molecule because of this drug
3 companies on route B because of this drug.
Companies on route B for this drug
In the product3 companies are on route B because of Dopamine.
See the 3 companies on route B for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Target
| Gene | Protein | UniProt |
|---|---|---|
| ADRB1 | Beta-1 adrenergic receptor | P08588 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 14 | 7 | 4 | 1 |
| Phase 1 | 3 | 1 | 0 | 1 |
| Phase 2 | 3 | 2 | 0 | 0 |
| Phase 3 | 3 | 1 | 0 | 1 |
| Phase 4 | 5 | 0 | 0 | 1 |
| All trials | 28 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| Astellas | Later holder | 1983 to now |
| Astra | Later holder | 1983 to now |
| B. Braun Medical | Later holder | 1986 to now |
| Baxter Healthcare | Acquired holder and Later holder | 1987 to now |
| International Medication System | Acquired holder | 2003 to now |
| Pfizer | Acquired holder and Later holder | 2003 to now |
| Lyphomed | Acquired holder | 2011 to now |
| Teligent Ou | Acquired holder | 2017 to now |
| BrePco Biopharma | Applicant | 2024 to now |
| Abbott | Later holder |