Drug

E-6201

As of the edition of 20 October 2026, E-6201 is a small molecule: stopped in 2025; acts on MAP2K1 and MAP3K1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2025
Kind
Small molecule
Registered trials
6, 3 stopped early
Disease areas
Cancer; Nervous system; Skin and connective tissue; Blood and lymph

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of E-6201.

Targets

GeneProteinUniProt
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1Q02750
MAP3K1Mitogen-activated protein kinase kinase kinase 1Q13233

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13102
Phase 23201
All trials6

Who ran its trials

CompanyRoleYears
EisaiLead sponsor of trials2007 to now
Spirita OncologyLead sponsor of trials2015 to now