Drug

Nedometinib

As of the edition of 20 October 2026, Nedometinib is a small molecule: stopped in 2024; acts on MAP2K1 and MAP2K2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2024
Kind
Small molecule
Registered trials
3, 1 stopped early
Disease areas
Cancer; Inherited and neonatal; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Nedometinib.

Targets

GeneProteinUniProt
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2P36507
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1Q02750

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 23201
All trials3

Who ran its trials

CompanyRoleYears
NFlection TherapeuticsLead sponsor of trials2020 to now