Drug

Etretinate

As of the edition of 20 October 2026, Etretinate is a small molecule: withdrawn from the market in 1989; acts on RARA, RARB and RARG and 3 more; no US protection is listed.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Withdrawn from market, 1989
Kind
Small molecule
Brand name
Tegison
First approved
30 September 1986 (US)
Approvals on record
2 in 1 region
Holder of the most recent approval
Roche
Withdrawn from market
1 January 1989 (in some regions)

US protection

No US protection is listed.

The FDA registers list no drug-substance patent or exclusivity that counts for this drug.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

3 company-target rows are on route B because of Etretinate.

Targets

GeneProteinUniProt
RARARetinoic acid receptor alphaP10276
RARBRetinoic acid receptor betaP10826
RARGRetinoic acid receptor gammaP13631
RXRARetinoic acid receptor RXR-alphaP19793
RXRBRetinoic acid receptor RXR-betaP28702
RXRGRetinoic acid receptor RXR-gammaP48443

Who has held its approvals

CompanyRoleYears
RocheOriginator1986 to now