Target

RXRG

Retinoic acid receptor RXR-gamma

As of the edition of 20 October 2026, RXRG (retinoic acid receptor RXR-gamma, UniProt P48443) has 5 drugs tested at it and 5 companies on the list, 2 on route A and 2 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P48443
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
Inside the cell
Solved structures
2
Disease areas
Cancer; Skin and connective tissue; Immune system; Blood and lymph; Lungs and airways; Infections; Urinary and reproductive; Digestive system
Registered trials of its drugs
76

Drugs at this target

StatusCount
Marketed3
Stopped1
Withdrawn from market1
Total5
DrugStatusFurthest phaseUS protection
BexaroteneMarketedPhase 4none listed
AcitretinMarketedPhase 4none listed
AlitretinoinMarketedPhase 3none listed
IRX-4204StoppedPhase 2none listed
EtretinateWithdrawn from marketNo phase statednone listed

5 of 5 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Route B2
Undetermined1
Total on the list5
Three companies on route A or B, with the route only
CompanyRoute
Bausch HealthRoute B
H.A.C. PharmaRoute B
Io TherapeuticsRoute A

The other 2 companies at RXRG

In the product

5 companies in all; 2 are not named here, and no score is.

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