GTI-2040
As of the edition of 20 October 2026, GTI-2040 is a drug: went quiet in 2010; acts on RRM2.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Went quiet, 2010
- Kind
- Unknown
- Registered trials
- 9, 0 stopped early
- Disease areas
- Cancer; Blood and lymph; Urinary and reproductive; Inherited and neonatal; Digestive system; Immune system
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Companies that need a new molecule because of this drug
1 company on route A because of this drug.
Companies on route A for this drug
In the product1 company is on route A because of GTI-2040.
See the 1 company on route A for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Target
| Gene | Protein | UniProt |
|---|---|---|
| RRM2 | Ribonucleoside-diphosphate reductase subunit M2 | P31350 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 1 | 4 | 4 | 0 | 0 |
| Phase 2 | 5 | 5 | 0 | 0 |
| All trials | 9 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| Aptose Biosciences | Lead sponsor of trials | 2002 to now |