Drug

Tezacitabine anhydrous

As of the edition of 20 October 2026, Tezacitabine anhydrous is a small molecule: went quiet in 2004; acts on RRM1, RRM2 and RRM2B.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2004
Kind
Small molecule
Registered trials
3, 1 stopped early
Disease areas
Cancer; Digestive system; Blood and lymph

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route A because of this drug.

Companies on route A for this drug

In the product

1 company-target row is on route A because of Tezacitabine anhydrous.

Targets

GeneProteinUniProt
RRM1Ribonucleoside-diphosphate reductase large subunitP23921
RRM2Ribonucleoside-diphosphate reductase subunit M2P31350
RRM2BRibonucleoside-diphosphate reductase subunit M2 BQ7LG56

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 22101
All trials3

Who ran its trials

CompanyRoleYears
NovartisLead sponsor of trials2003 to now