GTS-21
As of the edition of 20 October 2026, GTS-21 is a small molecule: stopped in 2016; acts on CHRNA7.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Stopped, 2016
- Kind
- Small molecule
- Registered trials
- 7, 1 stopped early
- Disease areas
- Mental health; Nervous system; Nutrition and metabolism
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Target
| Gene | Protein | UniProt |
|---|---|---|
| CHRNA7 | Neuronal acetylcholine receptor subunit alpha-7 | P36544 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 1 | 4 | 3 | 0 | 1 |
| Phase 2 | 3 | 3 | 0 | 0 |
| All trials | 7 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| CoMentis | Lead sponsor of trials | 2006 to now |