CHRNA7
Neuronal acetylcholine receptor subunit alpha-7
As of the edition of 20 October 2026, CHRNA7 (neuronal acetylcholine receptor subunit alpha-7, UniProt P36544) has 16 drugs tested at it and 15 companies on the list, 13 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P36544
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- At a membrane
- Solved structures
- 53
- Disease areas
- Mental health; Nervous system; Lungs and airways; Immune system; Nutrition and metabolism; Chemically induced; Hormones; Pregnancy and women's health
- Registered trials of its drugs
- 80
Drugs at this target
| Status | Count |
|---|---|
| Active | 1 |
| Went quiet | 6 |
| Stopped | 9 |
| Total | 16 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Encenicline | Stopped | Phase 3 | none listed |
| ABT-126 | Stopped | Phase 2 | none listed |
| AQW051 | Stopped | Phase 2 | none listed |
| GTS-21 | Stopped | Phase 2 | none listed |
| JNJ-39393406 | Went quiet | Phase 2 | none listed |
| AZD0328 | Stopped | Phase 2 | none listed |
| BNC-210 | Active | Phase 3 | none listed |
| Bradanicline | Went quiet | Phase 2 | none listed |
| ASM-024 | Stopped | Phase 2 | none listed |
| Facinicline | Went quiet | Phase 2 | none listed |
| APN1125 | Stopped | Phase 2 | none listed |
| AVL-3288 | Stopped | Phase 1 | none listed |
12 of 16 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 13 |
| Engaged | 2 |
| Total on the list | 15 |
| Company | Route |
|---|---|
| Roche | Route A |
| AstraZeneca | Route A |
| Novartis | Route A |
The other 12 companies at CHRNA7
In the product15 companies in all; 12 are not named here, and no score is.
See the 15 companies at CHRNA7, ranked, with the facts behind eachRequest access. Nothing is shown until you do.