Drug

RO5313534

As of the edition of 20 October 2026, RO5313534 is a drug known only by a code name: went quiet in 2010; acts on CHRNA7, HTR3A and HTR3B and 3 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2010
Kind
Code name only
Registered trials
2, 0 stopped early
Disease areas
Mental health; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route B and 5 company-target rows on route A because of this drug.

Companies on route B for this drug

In the product

1 company-target row is on route B because of RO5313534.

Companies on route A for this drug

In the product

5 company-target rows are on route A because of RO5313534.

Targets

GeneProteinUniProt
HTR3E5-hydroxytryptamine receptor 3EA5X5Y0
HTR3B5-hydroxytryptamine receptor 3BO95264
CHRNA7Neuronal acetylcholine receptor subunit alpha-7P36544
HTR3A5-hydroxytryptamine receptor 3AP46098
HTR3D5-hydroxytryptamine receptor 3DQ70Z44
HTR3C5-hydroxytryptamine receptor 3CQ8WXA8

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 21100
All trials2

Who ran its trials

CompanyRoleYears
RocheLead sponsor of trials2009 to now