Drug

Kw-2450 free base

As of the edition of 20 October 2026, Kw-2450 free base is a small molecule: stopped in 2012; acts on IGF1R and INSR.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2012
Kind
Small molecule
Registered trials
2, 1 stopped early
Disease areas
Cancer; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Kw-2450 free base.

Targets

GeneProteinUniProt
INSRInsulin receptorP06213
IGF1RInsulin-like growth factor 1 receptorP08069

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12101
All trials2

Who ran its trials

CompanyRoleYears
Kyowa KirinLead sponsor of trials2009 to now