Drug

Methazolamide

As of the edition of 20 October 2026, Methazolamide is a small molecule: marketed, first approved in 1982 (US); acts on CA1, CA2 and CA7; no US protection is listed.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Marketed; latest approval 1982
Kind
Small molecule
Brand name
Neptazane
First approved
1 January 1982 (US)
Approvals on record
2 in 1 region
Holder of the most recent approval
Pfizer
Registered trials
7, 3 stopped early
Disease areas
Lungs and airways; Cancer; Eye; Heart and blood vessels; Nervous system; Pregnancy and women's health

US protection

No US protection is listed.

The FDA registers list no drug-substance patent or exclusivity that counts for this drug.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

3 company-target rows are on route B because of Methazolamide.

Targets

GeneProteinUniProt
CA1Carbonic anhydrase 1P00915
CA2Carbonic anhydrase 2P00918
CA7Carbonic anhydrase 7P43166

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 22002
Phase 31001
Phase 44400
All trials7

Who has held its approvals

CompanyRoleYears
PfizerApplicant