Target

CA1

Carbonic anhydrase 1

As of the edition of 20 October 2026, CA1 (carbonic anhydrase 1, UniProt P00915) has 5 drugs tested at it and 9 companies on the list, 0 on route A and 3 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P00915
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
Inside the cell
Solved structures
57
Disease areas
Lungs and airways; Nervous system; Heart and blood vessels; Nutrition and metabolism; Eye; Inherited and neonatal; Mental health; Hormones
Registered trials of its drugs
107

Drugs at this target

StatusCount
Marketed5
Total5
DrugStatusFurthest phaseUS protection
AcetazolamideMarketedPhase 4none listed
MethazolamideMarketedPhase 4none listed
MethocarbamolMarketedPhase 4none listed
PolmacoxibMarketedPhase 3none listed
DichlorphenamideMarketedPhase 3none listed

5 of 5 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B3
Undetermined6
Total on the list9
Three companies on route A or B, with the route only
CompanyRoute
União Química Farmacêutica Nacional S/ARoute B
CrystalGenomicsRoute B
PfizerRoute B

The other 6 companies at CA1

In the product

9 companies in all; 6 are not named here, and no score is.

See the 9 companies at CA1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.