CA2
Carbonic anhydrase 2
As of the edition of 20 October 2026, CA2 (carbonic anhydrase 2, UniProt P00918) has 7 drugs tested at it and 16 companies on the list, 0 on route A and 9 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P00918
- How well studied
- Drug target: an approved drug acts on it
- Where it sits in the cell
- In more than one place
- Solved structures
- 1,259
- Disease areas
- Nervous system; Eye; Mental health; Nutrition and metabolism; Heart and blood vessels; Chemically induced; Lungs and airways; Hormones
- Registered trials of its drugs
- 387
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 7 |
| Total | 7 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Topiramate | Marketed | Phase 4 | none listed |
| Acetazolamide | Marketed | Phase 4 | none listed |
| Brinzolamide | Marketed | Phase 4 | none listed |
| Dorzolamide | Marketed | Phase 4 | none listed |
| Methazolamide | Marketed | Phase 4 | none listed |
| Polmacoxib | Marketed | Phase 3 | none listed |
| Dichlorphenamide | Marketed | Phase 3 | none listed |
7 of 7 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route B | 9 |
| Engaged | 3 |
| Undetermined | 4 |
| Total on the list | 16 |
| Company | Route |
|---|---|
| Merck & Co. | Route B |
| Novartis | Route B |
| Pfizer | Route B |
The other 13 companies at CA2
In the product16 companies in all; 13 are not named here, and no score is.
See the 16 companies at CA2, ranked, with the facts behind eachRequest access. Nothing is shown until you do.