Drug

Methohexital

As of the edition of 20 October 2026, Methohexital is a small molecule: marketed, first approved in 1982 (US); acts on GABRB1, GABRB2 and GABRB3; no US protection is listed.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Marketed; latest approval 1982
Kind
Small molecule
Brand name
Brevital Sodium
First approved
1 January 1982 (US)
Approvals on record
4 in 1 region
Holder of the most recent approval
Ph Health
Registered trials
3, 0 stopped early
Disease areas
Heart and blood vessels

US protection

No US protection is listed.

The FDA registers list no drug-substance patent or exclusivity that counts for this drug.

This is the US only.

Targets

GeneProteinUniProt
GABRB1Gamma-aminobutyric acid receptor subunit beta-1P18505
GABRB3Gamma-aminobutyric acid receptor subunit beta-3P28472
GABRB2Gamma-aminobutyric acid receptor subunit beta-2P47870

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1100
Phase 42200
All trials3

Who has held its approvals

CompanyRoleYears
Ph HealthAcquired holder2025 to now
Eli LillyEarlier holder