Target

MMP14

Matrix metalloproteinase-14

As of the edition of 20 October 2026, MMP14 (matrix metalloproteinase-14, UniProt P50281) has 1 drug tested at it and 1 company on the list, 1 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P50281
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
12
Disease areas
Cancer; Urinary and reproductive; Infections; Lungs and airways; Skin and connective tissue
Registered trials of its drugs
5

Drugs at this target

StatusCount
Stopped1
Total1
DrugStatusFurthest phaseUS protection
RebimastatStoppedPhase 3none listed

1 of 1 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Total on the list1
Three companies on route A or B, with the route only
CompanyRoute
Bristol Myers SquibbRoute A

The other 0 companies at MMP14

In the product

1 company in all; 0 are not named here, and no score is.

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