Drug

Traxoprodil

As of the edition of 20 October 2026, Traxoprodil is a small molecule: went quiet in 2006; acts on GRIN1 and GRIN2B.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2006
Kind
Small molecule
Registered trials
3, 1 stopped early
Disease areas
Nervous system; Heart and blood vessels; Mental health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

2 company-target rows are on route B because of Traxoprodil.

Targets

GeneProteinUniProt
GRIN1Glutamate receptor ionotropic, NMDA 1Q05586
GRIN2BGlutamate receptor ionotropic, NMDA 2BQ13224

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 23201
All trials3

Who ran its trials

CompanyRoleYears
PfizerLead sponsor of trials2003 to now