Drug

Vantictumab

As of the edition of 20 October 2026, Vantictumab is an antibody: went quiet in 2017; acts on FZD1, FZD2 and FZD5 and 2 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2017
Kind
Antibody
Registered trials
4, 0 stopped early
Disease areas
Cancer; Digestive system; Hormones; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

5 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

5 company-target rows are on route A because of Vantictumab.

Targets

GeneProteinUniProt
FZD7Frizzled-7O75084
FZD5Frizzled-5Q13467
FZD2Frizzled-2Q14332
FZD8Frizzled-8Q9H461
FZD1Frizzled-1Q9UP38

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 14400
All trials4

Who ran its trials

CompanyRoleYears
Mereo BioPharmaLead sponsor of trials2011 to now