Target

FZD1

Frizzled-1

As of the edition of 20 October 2026, FZD1 (frizzled-1, UniProt Q9UP38) has 1 drug tested at it and 1 company on the list, 1 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q9UP38
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
2
Disease areas
Cancer; Digestive system; Hormones; Skin and connective tissue
Registered trials of its drugs
4

Drugs at this target

StatusCount
Went quiet1
Total1
DrugStatusFurthest phaseUS protection
VantictumabWent quietPhase 1none listed

1 of 1 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Total on the list1
Three companies on route A or B, with the route only
CompanyRoute
Mereo BioPharmaRoute A

The other 0 companies at FZD1

In the product

1 company in all; 0 are not named here, and no score is.

See the 1 companies at FZD1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.