ADORA1
Adenosine receptor A1
As of the edition of 20 October 2026, ADORA1 (adenosine receptor A1, UniProt P30542) has 17 drugs tested at it and 21 companies on the list, 7 on route A and 8 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P30542
- How well studied
- Drug target: an approved drug acts on it
- Where it sits in the cell
- At a membrane
- Solved structures
- 5
- Disease areas
- Heart and blood vessels; Lungs and airways; Nervous system; Urinary and reproductive; Pregnancy and women's health; Immune system; Nutrition and metabolism; Infections
- Registered trials of its drugs
- 480
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 5 |
| Active | 1 |
| Went quiet | 7 |
| Stopped | 4 |
| Total | 17 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Caffeine | Marketed | Phase 4 | none listed |
| Theophylline anhydrous | Marketed | Phase 4 | none listed |
| Adenosine | Marketed | Phase 4 | none listed |
| Defibrotide | Marketed | Phase 4 | none listed |
| PBF-680 | Active | Phase 2 | none listed |
| BAY1067197 | Stopped | Phase 2 | none listed |
| Rolofylline | Went quiet | Phase 3 | none listed |
| Trabodenoson | Went quiet | Phase 3 | none listed |
| Derenofylline | Stopped | Phase 2 | none listed |
| Tonapofylline | Stopped | Phase 3 | none listed |
| Capadenoson | Went quiet | Phase 2 | none listed |
| KW-3902IV | Went quiet | Phase 2 | none listed |
12 of 17 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 7 |
| Route B | 8 |
| Engaged | 3 |
| Undetermined | 3 |
| Total on the list | 21 |
The other 18 companies at ADORA1
In the product21 companies in all; 18 are not named here, and no score is.
See the 21 companies at ADORA1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.