Target

CACNA1B

Voltage-dependent N-type calcium channel subunit alpha-1B

As of the edition of 20 October 2026, CACNA1B (voltage-dependent N-type calcium channel subunit alpha-1B, UniProt Q00975) has 7 drugs tested at it and 13 companies on the list, 3 on route A and 3 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q00975
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
7
Disease areas
Nervous system; Mental health; Cancer; Blood and lymph; Chemically induced; Heart and blood vessels; Immune system; Inherited and neonatal
Registered trials of its drugs
220

Drugs at this target

StatusCount
Marketed3
Went quiet3
Status not established1
Total7
DrugStatusFurthest phaseUS protection
LevetiracetamMarketedPhase 4none listed
ZiconotideMarketedPhase 4none listed
CNV2197944Went quietPhase 2none listed
RalfinamideWent quietPhase 3none listed
YHD1119Status not establishedPhase 1none listed
Z160Went quietPhase 2none listed
Ziconotide acetateMarketedNo phase statednone listed

7 of 7 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A3
Route B3
Engaged5
Undetermined2
Total on the list13
Three companies on route A or B, with the route only
CompanyRoute
Esteve PharmaceuticalsRoute B
Aché Laboratórios FarmacêuticosRoute B
Newron PharmaceuticalsRoute A

The other 10 companies at CACNA1B

In the product

13 companies in all; 10 are not named here, and no score is.

See the 13 companies at CACNA1B, ranked, with the facts behind eachRequest access. Nothing is shown until you do.