CDK7
Cyclin-dependent kinase 7
As of the edition of 20 October 2026, CDK7 (cyclin-dependent kinase 7, UniProt P50613) has 10 drugs tested at it and 14 companies on the list, 8 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P50613
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- Inside the cell
- Solved structures
- 56
- Disease areas
- Cancer; Blood and lymph; Immune system; Digestive system; Skin and connective tissue; Hormones; Inherited and neonatal; Urinary and reproductive
- Registered trials of its drugs
- 86
Drugs at this target
| Status | Count |
|---|---|
| Active | 4 |
| Went quiet | 1 |
| Stopped | 5 |
| Total | 10 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Alvocidib | Stopped | Phase 2 | none listed |
| CT-7001 | Active | Phase 2 | none listed |
| Seliciclib | Stopped | Phase 2 | none listed |
| BMS-387032 | Went quiet | Phase 1 | none listed |
| SY-5609 | Active | Phase 1 | none listed |
| LY3405105 | Stopped | Phase 1 | none listed |
| Q901 | Active | Phase 2 | none listed |
| TP-1287 | Stopped | Phase 1 | none listed |
| TY-2699a | Active | Phase 1 | none listed |
| XL102 | Stopped | Phase 1 | none listed |
10 of 10 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 8 |
| Engaged | 6 |
| Total on the list | 14 |
The other 11 companies at CDK7
In the product14 companies in all; 11 are not named here, and no score is.
See the 14 companies at CDK7, ranked, with the facts behind eachRequest access. Nothing is shown until you do.