Drug

Alvocidib

As of the edition of 20 October 2026, Alvocidib is a small molecule: stopped in 2021; acts on CDK1, CDK2 and CDK4 and 3 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2021
Kind
Small molecule
Registered trials
64, 13 stopped early
Disease areas
Cancer; Blood and lymph; Immune system; Inherited and neonatal; Urinary and reproductive; Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

18 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

18 company-target rows are on route A because of Alvocidib.

Targets

GeneProteinUniProt
CDK1Cyclin-dependent kinase 1P06493
CDK4Cyclin-dependent kinase 4P11802
CDK2Cyclin-dependent kinase 2P24941
CDK7Cyclin-dependent kinase 7P50613
CDK9Cyclin-dependent kinase 9P50750
CDK6Cyclin-dependent kinase 6Q00534

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 1332607
Phase 2312506
All trials64

Who ran its trials

CompanyRoleYears
SanofiLead sponsor of trials2007 to now
Sumitomo PharmaLead sponsor of trials2016 to now
AbbVieLead sponsor of trials2018 to now