Probatebeta
Target

CNR1

Cannabinoid receptor 1

As of the edition of 20 October 2026, CNR1 (cannabinoid receptor 1, UniProt P21554) has 17 drugs tested at it and 19 companies on the list, 6 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P21554
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
34
Disease areas
Mental health; Nervous system; Chemically induced; Nutrition and metabolism; Inherited and neonatal; Cancer; Hormones; Bones, joints and muscles
Registered trials of its drugs
485

Drugs at this target

StatusCount
Marketed3
Active2
Went quiet3
Stopped5
Withdrawn from market1
Status not established3
Total17
DrugStatusFurthest phaseUS protection
CannabidiolMarketedPhase 4Ends 2039
DronabinolMarketedPhase 4none listed
RimonabantWithdrawn from marketPhase 4none listed
NabiloneMarketedPhase 4none listed
OtenabantWent quietPhase 3none listed
TaranabantStoppedPhase 3none listed
AEF0117Status not establishedPhase 2none listed
DrinabantStoppedPhase 2none listed
INV-202ActivePhase 2none listed
NimacimabActivePhase 2none listed
IbipinabantStoppedPhase 3none listed
RLS103StoppedPhase 1none listed

12 of 17 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A6
Route B1
Engaged4
Undetermined8
Total on the list19
Three companies on route A or B, with the route only
CompanyRoute
PfizerRoute A
Bristol Myers SquibbRoute A
Merck & Co.Route A

The other 16 companies at CNR1

In the product

19 companies in all; 16 are not named here, and no score is.

See the 19 companies at CNR1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.

More drugs at CNR1

Other targets in mental health

Companies holding approvals at CNR1