CRHR1
Corticotropin-releasing hormone receptor 1
As of the edition of 20 October 2026, CRHR1 (corticotropin-releasing hormone receptor 1, UniProt P34998) has 8 drugs tested at it and 8 companies on the list, 6 on route A and 1 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P34998
- How well studied
- Drug target: an approved drug acts on it
- Where it sits in the cell
- At a membrane
- Solved structures
- 11
- Disease areas
- Pregnancy and women's health; Urinary and reproductive; Hormones; Inherited and neonatal; Mental health; Nutrition and metabolism; Cancer; Digestive system
- Registered trials of its drugs
- 43
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 1 |
| Went quiet | 1 |
| Stopped | 5 |
| Status not established | 1 |
| Total | 8 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Emicerfont | Stopped | Phase 2 | none listed |
| Verucerfont | Stopped | Phase 2 | none listed |
| Crinecerfont | Marketed | Phase 3 | Ends 2043 |
| Tildacerfont | Stopped | Phase 2 | none listed |
| Corticorelin acetate | Stopped | Phase 3 | none listed |
| Corticorelin | Status not established | Phase 2 | none listed |
| Pexacerfont | Stopped | Phase 3 | none listed |
| ONO-2333MS | Went quiet | Phase 2 | none listed |
8 of 8 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 6 |
| Route B | 1 |
| Engaged | 1 |
| Total on the list | 8 |
| Company | Route |
|---|---|
| Bristol Myers Squibb | Route A |
| GSK | Route A |
| Neurocrine | Route B |
The other 5 companies at CRHR1
In the product8 companies in all; 5 are not named here, and no score is.
See the 8 companies at CRHR1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.