Target

AVPR1A

Vasopressin V1a receptor

As of the edition of 20 October 2026, AVPR1A (vasopressin V1a receptor, UniProt P37288) has 14 drugs tested at it and 19 companies on the list, 2 on route A and 2 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P37288
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
7
Disease areas
Pregnancy and women's health; Urinary and reproductive; Hormones; Digestive system; Heart and blood vessels; Mental health; Infections; Nervous system
Registered trials of its drugs
247

Drugs at this target

StatusCount
Marketed8
Active1
Went quiet3
Stopped2
Total14
DrugStatusFurthest phaseUS protection
DesmopressinMarketedPhase 4none listed
VasopressinMarketedPhase 4none listed
TerlipressinMarketedPhase 4Ends 2029
ConivaptanMarketedPhase 4none listed
BalovaptanStoppedPhase 3none listed
SRX246ActivePhase 2none listed
SelepressinStoppedPhase 3none listed
Argipressin tannateMarketedPhase 4none listed
PecavaptanWent quietPhase 2none listed
SRX251Went quietPhase 1none listed
RO-5028442Went quietPhase 1none listed
FelypressinMarketedNo phase statednone listed

12 of 14 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Route B2
Engaged1
Undetermined14
Total on the list19
Three companies on route A or B, with the route only
CompanyRoute
RocheRoute A
PfizerRoute B
BayerRoute A

The other 16 companies at AVPR1A

In the product

19 companies in all; 16 are not named here, and no score is.

See the 19 companies at AVPR1A, ranked, with the facts behind eachRequest access. Nothing is shown until you do.