EPCAM
Epithelial cell adhesion molecule
As of the edition of 20 October 2026, EPCAM (epithelial cell adhesion molecule, UniProt P16422) has 13 drugs tested at it and 12 companies on the list, 3 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P16422
- How well studied
- Biology documented; no tool compounds or approved drug yet
- Where it sits in the cell
- In more than one place
- Solved structures
- 2
- Disease areas
- Cancer; Pregnancy and women's health; Urinary and reproductive; Digestive system; Hormones; Lungs and airways; Blood and lymph; Chemically induced
- Registered trials of its drugs
- 38
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 1 |
| Active | 5 |
| Went quiet | 4 |
| Stopped | 2 |
| Status not established | 1 |
| Total | 13 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Catumaxomab | Marketed | Phase 3 | none listed |
| Adecatumumab | Active | Phase 2 | none listed |
| Edrecolomab | Stopped | Phase 3 | none listed |
| M701 | Active | Phase 3 | none listed |
| Oportuzumab monatox | Status not established | Phase 3 | none listed |
| Tucotuzumab celmoleukin | Went quiet | Phase 2 | none listed |
| BA3182 | Active | Phase 1 | none listed |
| CX-2051 | Active | Phase 1 | none listed |
| Citatuzumab bogatox | Stopped | Phase 1 | none listed |
| ING-1 | Went quiet | Phase 1 | none listed |
| KK2269 | Active | Phase 1 | none listed |
| MOC31-PE | Went quiet | Phase 1 | none listed |
12 of 13 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 3 |
| Engaged | 6 |
| Undetermined | 3 |
| Total on the list | 12 |
| Company | Route |
|---|---|
| Merck KGaA | Route A |
| Neovii Biotech | Route A |
| Xoma | Route A |
The other 9 companies at EPCAM
In the product12 companies in all; 9 are not named here, and no score is.
See the 12 companies at EPCAM, ranked, with the facts behind eachRequest access. Nothing is shown until you do.