EPHB4
Ephrin type-B receptor 4
As of the edition of 20 October 2026, EPHB4 (ephrin type-B receptor 4, UniProt P54760) has 2 drugs tested at it and 2 companies on the list, 2 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- P54760
- How well studied
- Chemical tools exist; no approved drug acts on it
- Where it sits in the cell
- At a membrane
- Solved structures
- 23
- Disease areas
- Eye; Hormones; Cancer; Digestive system; Heart and blood vessels; Pregnancy and women's health; Urinary and reproductive
- Registered trials of its drugs
- 4
Drugs at this target
| Status | Count |
|---|---|
| Stopped | 2 |
| Total | 2 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| JI-101 | Stopped | Phase 2 | none listed |
| TG100-801 | Stopped | Phase 2 | none listed |
2 of 2 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Route A | 2 |
| Total on the list | 2 |
| Company | Route |
|---|---|
| Jubilant Innovation | Route A |
| TargeGen | Route A |
The other 0 companies at EPHB4
In the product2 companies in all; 0 are not named here, and no score is.
See the 2 companies at EPHB4, ranked, with the facts behind eachRequest access. Nothing is shown until you do.