Target

PTGFR

Prostaglandin F2-alpha receptor

As of the edition of 20 October 2026, PTGFR (prostaglandin F2-alpha receptor, UniProt P43088) has 9 drugs tested at it and 18 companies on the list, 0 on route A and 10 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P43088
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
8
Disease areas
Eye; Skin and connective tissue; Heart and blood vessels; Inherited and neonatal; Hormones; Immune system; Pregnancy and women's health; Urinary and reproductive
Registered trials of its drugs
294

Drugs at this target

StatusCount
Marketed7
Went quiet1
Status not established1
Total9
DrugStatusFurthest phaseUS protection
BimatoprostMarketedPhase 4Ends 2031
LatanoprostMarketedPhase 4none listed
TravoprostMarketedPhase 4none listed
TafluprostMarketedPhase 4none listed
Latanoprostene bunodMarketedPhase 4Ends 2029
CarboprostMarketedPhase 1none listed
AL-12182Went quietPhase 2none listed
DinoprostMarketedNo phase statednone listed
EbopiprantStatus not establishedPhase 2none listed

9 of 9 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B10
Engaged6
Undetermined2
Total on the list18
Three companies on route A or B, with the route only
CompanyRoute
PfizerRoute B
NovartisRoute B
AbbVieRoute B

The other 15 companies at PTGFR

In the product

18 companies in all; 15 are not named here, and no score is.

See the 18 companies at PTGFR, ranked, with the facts behind eachRequest access. Nothing is shown until you do.