Target

FCGRT

IgG receptor FcRn large subunit p51

As of the edition of 20 October 2026, FCGRT (igG receptor FcRn large subunit p51, UniProt P55899) has 5 drugs tested at it and 7 companies on the list, 2 on route A and 3 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P55899
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
32
Disease areas
Immune system; Nervous system; Cancer; Eye; Skin and connective tissue; Blood and lymph; Hormones; Inherited and neonatal
Registered trials of its drugs
133

Drugs at this target

StatusCount
Marketed3
Stopped2
Total5
DrugStatusFurthest phaseUS protection
Efgartigimod alfaMarketedPhase 4Ends 2033
NipocalimabMarketedPhase 3Ends 2037
RozanolixizumabMarketedPhase 4Ends 2035
BatoclimabStoppedPhase 3none listed
OrilanolimabStoppedPhase 2none listed

5 of 5 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Route B3
Engaged2
Total on the list7
Three companies on route A or B, with the route only
CompanyRoute
AstraZenecaRoute A
Johnson & JohnsonRoute B
argenxRoute B

The other 4 companies at FCGRT

In the product

7 companies in all; 4 are not named here, and no score is.

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