Target

IL18

Interleukin-18

As of the edition of 20 October 2026, IL18 (interleukin-18, UniProt Q14116) has 3 drugs tested at it and 5 companies on the list, 0 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q14116
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
In more than one place
Solved structures
20
Disease areas
Immune system; Skin and connective tissue; Inherited and neonatal; Digestive system; Bones, joints and muscles; Heart and blood vessels; Blood and lymph; Cancer
Registered trials of its drugs
18

Drugs at this target

StatusCount
Active3
Total3
DrugStatusFurthest phaseUS protection
GSK-1070806ActivePhase 2none listed
CamoteskimabActivePhase 2none listed
Tadekinig alfaActivePhase 3none listed

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Engaged5
Total on the list5