Target

IL6R

Interleukin-6 receptor subunit alpha

As of the edition of 20 October 2026, IL6R (interleukin-6 receptor subunit alpha, UniProt P08887) has 5 drugs tested at it and 4 companies on the list, 0 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P08887
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
Secreted
Solved structures
10
Disease areas
Immune system; Skin and connective tissue; Bones, joints and muscles; Cancer; Lungs and airways; Blood and lymph; Infections; Heart and blood vessels
Registered trials of its drugs
528

Drugs at this target

StatusCount
Marketed3
Active1
Went quiet1
Total5
DrugStatusFurthest phaseUS protection
TocilizumabMarketedPhase 4Ends 2028
SarilumabMarketedPhase 4Ends 2029
SatralizumabMarketedPhase 4Ends 2032
VobarilizumabWent quietPhase 2none listed
LevilimabActivePhase 3none listed

5 of 5 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B1
Engaged3
Total on the list4
Three companies on route A or B, with the route only
CompanyRoute
SanofiRoute B

The other 3 companies at IL6R

In the product

4 companies in all; 3 are not named here, and no score is.

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