Target

SI

Sucrase-isomaltase, intestinal [Cleaved into: Sucrase

As of the edition of 20 October 2026, SI (sucrase-isomaltase, intestinal [Cleaved into: Sucrase, UniProt P14410) has 2 drugs tested at it and 4 companies on the list, 2 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P14410
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
2
Disease areas
Infections; Nutrition and metabolism; Hormones; Digestive system; Immune system; Urinary and reproductive; Heart and blood vessels
Registered trials of its drugs
17

Drugs at this target

StatusCount
Marketed1
Went quiet1
Total2
DrugStatusFurthest phaseUS protection
VogliboseMarketedPhase 4none listed
CelgosivirWent quietPhase 2none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A2
Undetermined2
Total on the list4
Three companies on route A or B, with the route only
CompanyRoute
SanofiRoute A
BioWest TherapeuticsRoute A

The other 2 companies at SI

In the product

4 companies in all; 2 are not named here, and no score is.

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