Target

TNFSF14

Tumor necrosis factor ligand superfamily member 14

As of the edition of 20 October 2026, TNFSF14 (tumor necrosis factor ligand superfamily member 14, UniProt O43557) has 2 drugs tested at it and 3 companies on the list, 3 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
O43557
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
In more than one place
Solved structures
7
Disease areas
Immune system; Bones, joints and muscles; Skin and connective tissue; Digestive system; Lungs and airways; Nervous system
Registered trials of its drugs
11

Drugs at this target

StatusCount
Stopped2
Total2
DrugStatusFurthest phaseUS protection
BaminerceptStoppedPhase 2none listed
QuisovalimabStoppedPhase 2none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A3
Total on the list3
Three companies on route A or B, with the route only
CompanyRoute
Avalo TherapeuticsRoute A
Aevi Genomic MedicineRoute A
BiogenRoute A

The other 0 companies at TNFSF14

In the product

3 companies in all; 0 are not named here, and no score is.

See the 3 companies at TNFSF14, ranked, with the facts behind eachRequest access. Nothing is shown until you do.