US protection ending in 2030: Nervous system
As of the edition of 20 October 2026, 31 drugs have US protection that ends in 2030 in nervous system; 23 of them have at least one company on route B because of it.
Sources: FDA Orange Book and Purple Book, other approval registers.
31 drugs
| Drug | US protection | Status | Holder | Target | Route B rows |
|---|---|---|---|---|---|
| Aceclidine | Ends 2030 (exclusivity) | Marketed | LENZ Therapeutics | 0 | |
| Aflibercept | Ends 2030 (orphan exclusivity) | Marketed | Regeneron | PGF, VEGFA | 4 |
| Atrasentan | Ends 2030 (exclusivity) | Marketed | Novartis | EDNRA | 1 |
| Axitinib | Ends 2030 (patent) | Marketed | Pfizer | FLT1, FLT4, KDR | 0 |
| Burosumab | Ends 2030 (computed from the first US licence) | Marketed | Kyowa Kirin | FGF23 | 1 |
| Calaspargase pegol | Ends 2030 (computed from the first US licence) | Marketed | Servier | 0 | |
| Casimersen | Ends 2030 (patent) | Marketed | Avi Biopharma | DMD | 0 |
| Cemiplimab | Ends 2030 (computed from the first US licence) | Marketed | Regeneron | PDCD1 | 2 |
| Cenegermin | Ends 2030 (computed from the first US licence) | Marketed | Dompé Farmaceutici | NTRK1, NTRK2, NTRK3 | 3 |
| Dabrafenib | Ends 2030 (patent) | Marketed | Novartis | BRAF | 1 |
| Doxecitine | Ends 2030 (exclusivity) | Marketed | UCB | 0 | |
| Eliglustat | Ends 2030 (patent) | Marketed | Sanofi | UGCG | 1 |
| Emapalumab | Ends 2030 (computed from the first US licence) | Marketed | Swedish Orphan Biovitrum | IFNG | 1 |
| Encorafenib | Ends 2030 (exclusivity) | Marketed | Pfizer | BRAF | 3 |
| Erenumab | Ends 2030 (computed from the first US licence) | Marketed | Amgen | CALCRL | 1 |
| Fremanezumab | Ends 2030 (computed from the first US licence) | Marketed | Teva | CALCA, CALCB | 4 |
| Galcanezumab | Ends 2030 (computed from the first US licence) | Marketed | Eli Lilly | CALCA, CALCB | 2 |
| Macimorelin | Ends 2030 (exclusivity) | Marketed | COSCIENS Biopharma | GHSR | 2 |
| Mogamulizumab | Ends 2030 (computed from the first US licence) | Marketed | Kyowa Kirin | CCR4 | 1 |
| Moxetumomab pasudotox | Ends 2030 (computed from the first US licence) | Marketed | AstraZeneca | CD22, EEF2 | 2 |
| Neratinib | Ends 2030 (patent) | Marketed | Puma Biotechnology | EGFR | 2 |
| Nusinersen | Ends 2030 (patent) | Marketed | Biogen | SMN2 | 1 |
| Pacritinib | Ends 2030 (patent) | Marketed | Swedish Orphan Biovitrum | FLT3, JAK2 | 2 |
| Pegvaliase | Ends 2030 (computed from the first US licence) | Marketed | Amicus Therapeutics | 0 | |
| Pimavanserin | Ends 2030 (patent) | Marketed | Acadia Pharmaceuticals | HTR2A | 1 |
| Raltegravir | Ends 2030 (patent) | Marketed | Merck & Co. | 0 | |
| Ravulizumab | Ends 2030 (computed from the first US licence) | Marketed | AstraZeneca | C5 | 0 |
| Sildenafil | Ends 2030 (exclusivity) | Marketed | Viatris | PDE5A | 3 |
| Tepotinib | Ends 2030 (patent) | Marketed | Merck KGaA | MET | 1 |
| Trametinib | Ends 2030 (patent) | Marketed | Novartis | MAP2K1, MAP2K2 | 2 |
| Vemurafenib | Ends 2030 (patent) | Marketed | Roche | BRAF | 1 |
Listed by name. A route B row is one company at one target; for a drug with one target that is the number of companies. US protection is the US only, and it is not the date generics or biosimilars can enter.
Which companies are on route B in 2030 in nervous system
In the product23 of these 31 drugs have at least one company on route B. Which companies, and their scores, are in the product.
Get this list with the companies, scores and sources as a fileRequest access. Nothing is shown until you do.