Drug

ACT-462206

As of the edition of 20 October 2026, ACT-462206 is a small molecule: went quiet in 2012; acts on HCRTR1 and HCRTR2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2012
Kind
Small molecule
Registered trials
1, 0 stopped early

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

2 company-target rows are on route B because of ACT-462206.

Targets

GeneProteinUniProt
HCRTR1Orexin/Hypocretin receptor type 1O43613
HCRTR2Orexin receptor type 2O43614

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
All trials1

Who ran its trials

CompanyRoleYears
Idorsia PharmaceuticalsLead sponsor of trials2011 to now