Drug

Almorexant

As of the edition of 20 October 2026, Almorexant is a small molecule: went quiet in 2014; acts on HCRTR1 and HCRTR2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2014
Kind
Small molecule
Registered trials
6, 0 stopped early
Disease areas
Mental health; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route B and 2 company-target rows on route A because of this drug.

Companies on route B for this drug

In the product

2 company-target rows are on route B because of Almorexant.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Almorexant.

Targets

GeneProteinUniProt
HCRTR1Orexin/Hypocretin receptor type 1O43613
HCRTR2Orexin receptor type 2O43614

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1100
Phase 13300
Phase 21100
Phase 31100
All trials6

Who ran its trials

CompanyRoleYears
Midnight PharmaLead sponsor of trials2006 to now
Idorsia PharmaceuticalsLead sponsor of trials2011 to now