Drug

Filorexant

As of the edition of 20 October 2026, Filorexant is a small molecule: stopped in 2013; acts on HCRTR1 and HCRTR2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2013
Kind
Small molecule
Registered trials
5, 1 stopped early
Disease areas
Nervous system; Mental health; Hormones

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

2 company-target rows are on route B because of Filorexant.

Targets

GeneProteinUniProt
HCRTR1Orexin/Hypocretin receptor type 1O43613
HCRTR2Orexin receptor type 2O43614

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 24301
All trials5

Who ran its trials

CompanyRoleYears
Merck & Co.Lead sponsor of trials2009 to now