Drug

Alvespimycin

As of the edition of 20 October 2026, Alvespimycin is a small molecule: stopped in 2012; acts on HSP90AA1 and HSP90AB1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2012
Kind
Small molecule
Registered trials
7, 2 stopped early
Disease areas
Cancer; Blood and lymph; Immune system; Skin and connective tissue; Heart and blood vessels; Infections

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Alvespimycin.

Targets

GeneProteinUniProt
HSP90AA1Heat shock protein HSP 90-alphaP07900
HSP90AB1Heat shock protein HSP 90-betaP08238

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 16401
Phase 21001
All trials7

Who ran its trials

CompanyRoleYears
Bristol Myers SquibbLead sponsor of trials2006 to now