Drug

Retaspimycin

As of the edition of 20 October 2026, Retaspimycin is a small molecule: went quiet in 2014; acts on HSP90AA1 and HSP90AB1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2014
Kind
Small molecule
Registered trials
12, 6 stopped early
Disease areas
Cancer; Lungs and airways; Skin and connective tissue; Digestive system; Blood and lymph; Heart and blood vessels

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of Retaspimycin.

Targets

GeneProteinUniProt
HSP90AA1Heat shock protein HSP 90-alphaP07900
HSP90AB1Heat shock protein HSP 90-betaP08238

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13300
Phase 28305
Phase 31001
All trials12

Who ran its trials

CompanyRoleYears
Infinity PharmaceuticalsLead sponsor of trials2005 to now
AstraZenecaLead sponsor of trials2008 to now