Drug

Luminespib

As of the edition of 20 October 2026, Luminespib is a small molecule: went quiet in 2019; acts on HSP90AA1 and HSP90AB1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2019
Kind
Small molecule
Registered trials
23, 7 stopped early
Disease areas
Cancer; Lungs and airways; Digestive system; Blood and lymph; Immune system; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of Luminespib.

Targets

GeneProteinUniProt
HSP90AA1Heat shock protein HSP 90-alphaP07900
HSP90AB1Heat shock protein HSP 90-betaP08238

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 16501
Phase 2171006
All trials23

Who ran its trials

CompanyRoleYears
NovartisLead sponsor of trials2007 to now
SCRI Development InnovationsLead sponsor of trials2011 to now