Drug

AT-13148

As of the edition of 20 October 2026, AT-13148 is a small molecule: went quiet in 2018; acts on MAPKAPK2, ROCK1 and ROCK2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2018
Kind
Small molecule
Registered trials
1, 0 stopped early
Disease areas
Cancer

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
ROCK2Rho-associated protein kinase 2O75116
MAPKAPK2MAP kinase-activated protein kinase 2P49137
ROCK1Rho-associated protein kinase 1Q13464

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
All trials1