Netarsudil
As of the edition of 20 October 2026, Netarsudil is a small molecule: marketed, first approved in 2017 (US); acts on ROCK1 and ROCK2; US protection ends in 2034.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 2023
- Kind
- Small molecule
- Brand name
- Rhopressa
- First approved
- 18 December 2017 (US)
- Approvals on record
- 4 in 3 regions
- Holder of the most recent approval
- Santen Pharmaceutical; 3 holders in all
- Registered trials
- 32, 1 stopped early
- Disease areas
- Eye; Inherited and neonatal; Nervous system
US protection
US protection ends in 2034.
The last listed US drug-substance patent ends in 2034. The application that gives this date is held by Alcon.
This is the US only, and it is not the date generics or biosimilars can enter.
The exact date and the listings behind it
In the product8 listings count towards this date. The exact date and each listing are in the product.
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Companies that need a new molecule because of this drug
6 company-target rows on route B because of this drug.
Companies on route B for this drug
In the product6 company-target rows are on route B because of Netarsudil.
See the 6 company-target rows on route B for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Targets
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 2 | 1 | 1 | 0 |
| Phase 1 | 5 | 4 | 0 | 0 |
| Phase 2 | 8 | 7 | 1 | 0 |
| Phase 3 | 10 | 8 | 0 | 1 |
| Phase 4 | 7 | 2 | 4 | 0 |
| All trials | 32 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| Alcon | Originator, Applicant and Lead sponsor of trials | 2012 to now |
| Santen | Applicant | 2019 to now |
| Santen Pharmaceutical | Applicant | 2023 to now |