Drug

Doxazosin

As of the edition of 20 October 2026, Doxazosin is a small molecule: marketed, first approved in 1990 (ES); acts on ADRA1A, ADRA1B and ADRA1D.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Marketed; latest approval 1999
Kind
Small molecule
Brand name
Cardura
First approved
1 November 1990 (ES)
Approvals on record
8 in 3 regions
Holder of the most recent approval
Viatris; 3 holders in all
Registered trials
33, 3 stopped early
Disease areas
Mental health; Chemically induced; Heart and blood vessels; Urinary and reproductive; Pregnancy and women's health; Hormones

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

6 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

6 company-target rows are on route B because of Doxazosin.

Targets

GeneProteinUniProt
ADRA1DAlpha-1D adrenergic receptorP25100
ADRA1AAlpha-1A adrenergic receptorP35348
ADRA1BAlpha-1B adrenergic receptorP35368

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated5202
Phase 16501
Phase 211810
Phase 33300
Phase 48800
All trials33

Who has held its approvals

CompanyRoleYears
ViatrisAcquired holder2022 to now
PfizerOriginator1990 to 2022