Drug

Prazosin

As of the edition of 20 October 2026, Prazosin is a small molecule: marketed, first approved in 1979 (ES); acts on ADRA1A, ADRA1B and ADRA1D.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Marketed; latest approval 1988
Kind
Small molecule
Brand name
Minipress
First approved
1 December 1979 (ES)
Approvals on record
13 in 4 regions
Holder of the most recent approval
Pfizer; 2 holders in all
Registered trials
40, 6 stopped early
Disease areas
Mental health; Chemically induced; Nervous system; Heart and blood vessels; Digestive system; Infections

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

3 company-target rows are on route B because of Prazosin.

Targets

GeneProteinUniProt
ADRA1DAlpha-1D adrenergic receptorP25100
ADRA1AAlpha-1A adrenergic receptorP35348
ADRA1BAlpha-1B adrenergic receptorP35368

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated12704
Phase 16500
Phase 212831
Phase 32110
Phase 48601
All trials40

Who has held its approvals

CompanyRoleYears
PfizerApplicant and Lead sponsor of trials2021 to now