Drug

Ebvaciclib

As of the edition of 20 October 2026, Ebvaciclib is a small molecule: stopped in 2024; acts on CDK2, CDK4 and CDK6.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2024
Kind
Small molecule
Registered trials
1, 1 stopped early
Disease areas
Cancer; Hormones; Pregnancy and women's health; Skin and connective tissue; Urinary and reproductive

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

2 company-target rows are on route B because of Ebvaciclib.

Targets

GeneProteinUniProt
CDK4Cyclin-dependent kinase 4P11802
CDK2Cyclin-dependent kinase 2P24941
CDK6Cyclin-dependent kinase 6Q00534

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 21001
All trials1

Who ran its trials

CompanyRoleYears
PfizerLead sponsor of trials2018 to now