Drug

Isoproterenol

As of the edition of 20 October 2026, Isoproterenol is a small molecule: marketed, first approved in 1969 (ES); acts on ADRB1, ADRB2 and ADRB3.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Marketed; latest approval 2020
Kind
Small molecule
Brand name
Isuprel
First approved
1 January 1969 (ES)
Approvals on record
18 in 3 regions
Holder of the most recent approval
MARCAN PHARMACEUTICALS INC; 10 holders in all
Registered trials
17, 0 stopped early
Disease areas
Heart and blood vessels; Nervous system; Cancer; Mental health; Pregnancy and women's health; Urinary and reproductive

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route B and 2 company-target rows on route A because of this drug.

Companies on route B for this drug

In the product

3 company-target rows are on route B because of Isoproterenol.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Isoproterenol.

Targets

GeneProteinUniProt
ADRB2Beta-2 adrenergic receptorP07550
ADRB1Beta-1 adrenergic receptorP08588
ADRB3Beta-3 adrenergic receptorP13945

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated8520
Phase 14130
Phase 23200
Phase 42020
All trials17

Who has held its approvals

CompanyRoleYears
AbbottAcquired holder and Later holder2003 to now
AbbVieAcquired holder2012 to now
Bausch HealthAcquired holder2019 to now
3MLater holder
Eli LillyLater holder
FisonsLater holder
SanofiLater holder