Drug

MK-2206

As of the edition of 20 October 2026, MK-2206 is a small molecule: stopped in 2018; acts on AKT1, AKT2 and AKT3.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2018
Kind
Small molecule
Registered trials
43, 13 stopped early
Disease areas
Cancer; Skin and connective tissue; Digestive system; Urinary and reproductive; Blood and lymph; Pregnancy and women's health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
AKT1RAC-alpha serine/threonine-protein kinaseP31749
AKT2RAC-beta serine/threonine-protein kinaseP31751
AKT3RAC-gamma serine/threonine-protein kinaseQ9Y243

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 115914
Phase 2281909
All trials43

Who ran its trials

CompanyRoleYears
Merck & Co.Lead sponsor of trials2008 to now