Perifosine
As of the edition of 20 October 2026, Perifosine is a small molecule: went quiet in 2021; acts on AKT1.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Went quiet, 2021
- Kind
- Small molecule
- Registered trials
- 40, 3 stopped early
- Disease areas
- Cancer; Blood and lymph; Immune system; Urinary and reproductive; Digestive system; Heart and blood vessels
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Companies that need a new molecule because of this drug
1 company on route A because of this drug.
Companies on route A for this drug
In the product1 company is on route A because of Perifosine.
See the 1 company on route A for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Target
| Gene | Protein | UniProt |
|---|---|---|
| AKT1 | RAC-alpha serine/threonine-protein kinase | P31749 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 1 | 1 | 0 | 0 |
| Phase 1 | 15 | 15 | 0 | 0 |
| Phase 2 | 23 | 21 | 0 | 2 |
| Phase 3 | 1 | 0 | 0 | 1 |
| All trials | 40 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| COSCIENS Biopharma | Lead sponsor of trials | 2004 to now |